After more than four decades of participation in the majority of elements of direction, from identifying, qualifying, training, developing and consulting leaders, to functioning, as a leader, for all associations (small and large), I have frequently been asked, what I think, to be, the most significant consideration of principle, of leading efficiently. I’ve discovered, and learned, whether it’s likely to teach someone, and supply them with the necessary and essential skills, to proceed, wisely, one must begin the procedure, using a specific kind of mindset, and attitude. In case that had to be summed – up, only, and of course, it’d be, one must be directed by the heart principle, todo, what’s appropriate! Bearing that in mind, this article will attempt to briefly examine, consider, and talk, with the mnemonic strategy, why understanding human nature. And/ or what causes us, what we do, is most essential and relevant. It is vital to move in a righteous fashion, without having to be self – righteous! Just how could you know what is relevant, until/ unless he pays keen attention, to both the strengths and weaknesses, and the positives, in addition to negatives? Leading must focus on being responsive to demands, goals, priorities, and also the mission of the bunch! A pioneer is accountable for effective leadership preparation, and seeking strategic and action plans, with sustainability, and understanding ramifications, as core components.