After more than four years of participation in nearly all aspects of direction, by identifying, qualifying, training, consulting and developing leaders, to serving, as a pioneer, for all organizations (large and small), I’ve often been asked, what I consider, to be, the most significant consideration of rule, of leading efficiently. I have discovered, and heard, while it’s likely to train somebody, and furnish them, with the necessary and essential skills, to move, wisely, an individual must begin the process, with a particular type of mindset, and also attitude. If that must be summed – up, only, and of course, it would be, an individual must be guided by the core principle, to do, what’s perfect! Keeping that in mind, this article will try and briefly examine, consider, and discuss, with the mnemonic strategy, why understanding human nature. And/ or what makes us, that which we do, is important and important. Righteous; relevant; responsive; responsible; ramifications: It’s vital that you move, in a righteous fashion, without having to be self – righteous! Just how would one understand what is relevant, until/ unless he pays keen attention, to the strengths and flaws, and the positives, in addition to negatives? Leading must concentrate on being responsive to demands, aims, priorities, and the mission of this bunch! A leader is responsible for effective leadership planning, and hunting strategic and action plans, together with sustainability, and achieving ramifications, as core components.